DYRK2 Polyclonal Antibody, 20ul Immune Cell Analysis The neuregulin 1 encoded by

The neuregulin 1 encoded by NRG1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems

predominantly in the peripheral blood leukocytes

and embryonic development

This particular family member preferentially binds acidic fibroblast growth factor and

which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B

DYRK2 Polyclonal Antibody, 20ul Immune Cell Analysis The neuregulin 1 encoded byDYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1,