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GFAP Polyclonal Antibody, 50ul Protein Post-translational Modification The 9-1-1 complex stimulates DNA

SKU: 44905535551

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GFAP Polyclonal Antibody, 50ul Protein Post-translational Modification The 9-1-1 complex stimulates DNAGFAP encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Description

The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds

Multiple alternatively spliced variants encoding different isoforms have been described

pre-mRNA-splicing regulator WTAP is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors

It is used as a marker to distinguish astrocytes from other glial cells during development

It binds to IL8 with high affinity

GFAP Polyclonal Antibody, 50ul Protein Post-translational Modification The 9-1-1 complex stimulates DNAGFAP encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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