MEK2 Monoclonal Antibody(2C3), 20ul Dry Bath Several transcript variants encoding two

Several transcript variants encoding two different isoforms have been found for this gene

which is characterized by severe growth defects

a T-cell receptor

The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration

Post-translational modifications such as phosphorylation

MEK2 Monoclonal Antibody(2C3), 20ul Dry Bath Several transcript variants encoding twoThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1 ERK2 and MAPK2 ERK3. The activation of this kinase itself is dependent on the Ser Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC