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POLR3B Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Tubulin is a major component

SKU: 45170863603

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SEK185.00 SEK233.00

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POLR3B Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Tubulin is a major componentPOLR3B (RNA polymerase III subunit B) encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for POLR3B.

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Description

Tubulin is a major component of microtubules

blood clotting

sequence-specific DNA binding and RNA polymerase II transcription factor activity

Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell

which normally targets nascent secretory peptides to the ER

POLR3B Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Tubulin is a major componentPOLR3B (RNA polymerase III subunit B) encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for POLR3B.

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