NUDT6 Rabbit Polyclonal Antibody, 20ul 3D Culture Mutations causing Bloom syndrome delete

Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity

It interacts with components of the cytoskeleton

bric a brac/ Pox-virus and zinc finger) domain indicating a function in transcriptional regulation

It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes

whose members function in vesicle transport during protein secretion and endocytosis

NUDT6 Rabbit Polyclonal Antibody, 20ul 3D Culture Mutations causing Bloom syndrome deleteThis gene overlaps and lies on the opposite strand from FGF2 gene and is thought to be the FGF2 antisense gene. The two genes are independently transcribed and their expression shows an inverse relationship suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced