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Rb Monoclonal Antibody, 100ul Liquid Handling &Storage In response to interferon (IFN)

SKU: 45244320472

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Rb Monoclonal Antibody, 100ul Liquid Handling &Storage In response to interferon (IFN)The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

In response to interferon (IFN)

Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells

Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E| gamma-F| gamma-G) are tandemly organized in a genomic segment as a gene cluster

CLCN7 encodes chloride channel 7

An important paralog of this gene is SVOP

Rb Monoclonal Antibody, 100ul Liquid Handling &Storage In response to interferon (IFN)The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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