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IκB-beta(Phospho Ser23) Polyclonal Antibody, 20ul Mechanical Pipette |Responsible for the deacetylation of

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IκB-beta(Phospho Ser23) Polyclonal Antibody, 20ul Mechanical Pipette |Responsible for the deacetylation ofThe protein encoded by this gene belongs to the NF kappa B inhibitor family, which inhibit NF kappa B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been

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Description

|Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A| H2B| H3 and H4)

GABARAPL2 is strongly expressed in the brain

Seems to play a role as an inhibitor of apoptosis

Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation| and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization

and has been implicated in development of prostate cancer cells

IκB-beta(Phospho Ser23) Polyclonal Antibody, 20ul Mechanical Pipette |Responsible for the deacetylation ofThe protein encoded by this gene belongs to the NF kappa B inhibitor family, which inhibit NF kappa B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been

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