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PKR(Phospho Thr451) Polyclonal Antibody, 20ul Glassware Sets It is also a candidate

SKU: 45529986217

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PKR(Phospho Thr451) Polyclonal Antibody, 20ul Glassware Sets It is also a candidateThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome

Interaction of protein FADD with the receptors unmasks the N-terminal effector domain of this protein

PTM:Glycosylated

Mutations in PRKAR1A cause Carney complex (CNC)

It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development

PKR(Phospho Thr451) Polyclonal Antibody, 20ul Glassware Sets It is also a candidateThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

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