Rb Polyclonal Antibody, 20ul[BT-AP07688] Yeast Expression NEK9 (NIMA related kinase 9)

NEK9 (NIMA related kinase 9) encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases

three ANK repeats

It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer

This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system

An important paralog of this gene is UBA52

Rb Polyclonal Antibody, 20ul[BT-AP07688] Yeast Expression NEK9 (NIMA related kinase 9)The protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.