NELL2 Rabbit Polyclonal Antibody, 100ul Human Genome Knockout Libraries This gene is the cellular

This gene is the cellular homolog of viral raf gene (v-raf)

which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins

This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein

Alternative splicing has been observed at this locus and two variants

Diseases associated with SV2C include alcohol-related birth defect and foodborne botulism

NELL2 Rabbit Polyclonal Antibody, 100ul Human Genome Knockout Libraries This gene is the cellularThe protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF) like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in