JAK3 Polyclonal Antibody, 20ul Immunology This protein plays a role
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JAK3 Polyclonal Antibody, 20ul Immunology This protein plays a roleThe protein encoded by JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
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