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Net(Phospho Ser357) Polyclonal Antibody, 100ul Protein Expression but the encoded protein only

SKU: 45823469418

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PLN141.00 PLN175.00

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Net(Phospho Ser357) Polyclonal Antibody, 100ul Protein Expression but the encoded protein onlyThis gene encodes a member of the ETS domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate

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Description

but the encoded protein only shows sequence identity with the upstream gene product

Alternative splicing and alternative promoter usage results in multiple transcript variants

2001 [PubMed 11567032])

The activation is rapid and specific

which may contribute to its ability to reduce the tumorigenic phenotype in cells

Net(Phospho Ser357) Polyclonal Antibody, 100ul Protein Expression but the encoded protein onlyThis gene encodes a member of the ETS domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate

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