FoxO3a(Phospho-Ser7) Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene

The protein interacts with host cell factor C1

this protein inhibits p53 by binding its transcriptional activation domain

to DNA-damage foci

Mutations in this gene are associated with interleukin 2 receptor alpha deficiency

FoxO3a(Phospho-Ser7) Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases Multiple alternatively spliced transcript variantsThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.