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SFRP1 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) E3 ubiquitin-protein ligase UBR1 described

SKU: 45951620345

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SFRP1 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) E3 ubiquitin-protein ligase UBR1 describedThis gene encodes a member of the SFRP family that contains a cysteine rich domain homologous to the putative Wnt binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.

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Description

E3 ubiquitin-protein ligase UBR1 described in this record has a RING-type zinc finger and a UBR-type zinc finger

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SFRP1 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) E3 ubiquitin-protein ligase UBR1 describedThis gene encodes a member of the SFRP family that contains a cysteine rich domain homologous to the putative Wnt binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.

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