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CD6 Polyclonal Antibody, 100ul[BT-AP02136] Biomatrix Defects in this gene are

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CD6 Polyclonal Antibody, 100ul[BT-AP02136] Biomatrix Defects in this gene areCTTN is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. Cortactin is localized in the cytoplasm and in areas of the cell substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, cortactin is degraded in a caspase dependent manner. The

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Description

Defects in this gene are a cause of congenital secretory sodium diarrhea

MIM 601625) transfer ADP-ribose from NAD+ to the target protein

So far detected are isoform Alpha-6X1A| isoform Alpha-6X1B and isoform Alpha-6X1X2A (minor)

The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype

its substrate has not yet been determined

CD6 Polyclonal Antibody, 100ul[BT-AP02136] Biomatrix Defects in this gene areCTTN is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. Cortactin is localized in the cytoplasm and in areas of the cell substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, cortactin is degraded in a caspase dependent manner. The

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