Endothelin B Receptor Polyclonal Antibody, 50ul Primary Antibodies Multiple alternatively spliced variants| encoding

Multiple alternatively spliced variants| encoding the same protein| have been identified

This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus

Bim functions in regulating apoptosis associated with thymocyte negative selection and following growth factor withdrawal

TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity

The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1|4|5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors

Endothelin B Receptor Polyclonal Antibody, 50ul Primary Antibodies Multiple alternatively spliced variants| encodingThe protein encoded by this gene is a G protein coupled receptor which activates a phosphatidylinositol calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple