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SFRP4 Polyclonal Antibody, 100ul Peripheral Blood Separation Tube The encoded protein regulates signaling

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SFRP4 Polyclonal Antibody, 100ul Peripheral Blood Separation Tube The encoded protein regulates signalingSecreted frizzled related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine rich domain homologous to the putative Wnt binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression.

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Description

The encoded protein regulates signaling pathways that affect cell proliferation and adhesion

Defects in this gene are a cause of Bernard-Soulier syndrome

In response to cytokines and growth factors| STAT family members are phosphorylated by the receptor associated kinases| and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs

PVRL3 encodes a member of the nectin family of proteins

SFRP4 Polyclonal Antibody, 100ul Peripheral Blood Separation Tube The encoded protein regulates signalingSecreted frizzled related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine rich domain homologous to the putative Wnt binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression.

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