SC23A Rabbit Polyclonal Antibody, 50ul Microplate Mixer epigenetic silencing of SFRP genes

epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer

which are implicated in actin remodeling

Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis

4 Ampule/Tube Attachment

GO annotations related to this gene include enzyme binding and RNA polymerase II transcription corepressor activity

SC23A Rabbit Polyclonal Antibody, 50ul Microplate Mixer epigenetic silencing of SFRP genesThe protein encoded by this gene is a member of the SEC23 subfamily of the SEC23 SEC24 family. It is part of a protein complex and found in the ribosome free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER Golgi protein