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ANTR1 Polyclonal Antibody, 100ul Culture Tubes Alternative splicing of this gene

SKU: 46320747789

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DKK123.75 DKK159.75

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ANTR1 Polyclonal Antibody, 100ul Culture Tubes Alternative splicing of this geneThis gene encodes a type I transmembrane protein and is a tumor specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol

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Description

Alternative splicing of this gene results in two transcript variants

|Contains 9 SRCR domains

Among its related pathways are MAP Kinase Signaling andTGF-Beta Pathway

Mitogen-activated protein kinase 8 localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways

Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis

ANTR1 Polyclonal Antibody, 100ul Culture Tubes Alternative splicing of this geneThis gene encodes a type I transmembrane protein and is a tumor specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol

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