UBP20 Rabbit Polyclonal Antibody, 20ul Pipette Controller Three alternatively spliced transcript variants

Three alternatively spliced transcript variants that encode different protein isoforms have been described

sterilized by irradiationto SAL 10^-6

Aberrant expression of this gene may paly a role in tumorigenesis

This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells

The complex functions as a single-stranded DNA-dependent ATP-dependent helicase

UBP20 Rabbit Polyclonal Antibody, 20ul Pipette Controller Three alternatively spliced transcript variantsThis gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL E3 ligase complex this enzyme deubiquitinates hypoxia inducible factor (HIF) 1 alpha and thereby causes increased expression of HIF 1alpha targeted genes which play a role in angiogenesis glucose metabolism cell proliferation and