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PAK alpha(Phospho Ser199) Polyclonal Antibody, 50ul Virus Packaging Mutations in this gene are

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PAK alpha(Phospho Ser199) Polyclonal Antibody, 50ul Virus Packaging Mutations in this gene areThis gene encodes a family member of serine threonine p21 activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this

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Description

Mutations in this gene are associated with microphthalmia

MIM 604998) (Gardner et al

The encoded protein contains five WD-repeats spanning most of the protein and an SOCS box in the C-terminus

This protein may play a role in maintaining the differentiated state of muscle cells

Retinoic acid plays a critical role in development

PAK alpha(Phospho Ser199) Polyclonal Antibody, 50ul Virus Packaging Mutations in this gene areThis gene encodes a family member of serine threonine p21 activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this

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