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ASPP1 Polyclonal Antibody, 100ul Liquid Handling &Storage it also regulates the splicing

SKU: 46672425860

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ASPP1 Polyclonal Antibody, 100ul Liquid Handling &Storage it also regulates the splicingThis gene encodes a member of the ASPP (apoptosis stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein protein interactions. ASPP proteins are required for the induction of apoptosis by p53 family proteins. They promote DNA binding and transactivation of p53 family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F

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Description

it also regulates the splicing of fibronectin and CD45 genes

some members of which are clustered together on chromosome 12q13

This protein directly interacts with TNF receptors

|PTM:Phosphorylation by PKB/AKT1 inhibits transcriptional activity and is responsible for cytoplasmic localization

which have been implicated in the regulation of cytoskeletal dynamics

ASPP1 Polyclonal Antibody, 100ul Liquid Handling &Storage it also regulates the splicingThis gene encodes a member of the ASPP (apoptosis stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein protein interactions. ASPP proteins are required for the induction of apoptosis by p53 family proteins. They promote DNA binding and transactivation of p53 family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F

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