NVL Polyclonal Antibody, 50ul Culture Media Elongation factor 1-beta is a

Elongation factor 1-beta is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome

It also interacts with multiple proteins including calmodulin| CABP1| enkurin| Na(+)-H+ exchange regulatory factor (NHERF )| interferon-induced GTP-binding protein (MX1)| ring finger protein 24 (RNF24)| and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1)

the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein

miscellaneous:The gene maps to 3q26

it is seen within the basement membrane of the dermal-epidermal junction at points of nerve penetration

NVL Polyclonal Antibody, 50ul Culture Media Elongation factor 1-beta is aNVL encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983,