Histone H2B Polyclonal Antibody, 100ul[BT-AP04029] Mammalian Expression Its gene product is believed

Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases

Many members of the forkhead box gene family| including members of subfamily P| have roles in mammalian oncogenesis

The resulting trimer binds to DNA with high specificity and affinity

This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT)

2003 [PubMed 14508493])

Histone H2B Polyclonal Antibody, 100ul[BT-AP04029] Mammalian Expression Its gene product is believedH2BFS is a Pseudogene. Histone H2B type 1 H is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones, also called histone