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KLF14 Polyclonal Antibody, 100ul Peptide Synthesis Could be E3 ubiquitin-protein ligase

SKU: 46916095506

4.6
PLN123.75 PLN145.75

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KLF14 Polyclonal Antibody, 100ul Peptide Synthesis Could be E3 ubiquitin-protein ligaseThis intronless gene encodes a member of the Kruppel like family of transcription factors. The encoded protein functions as a transcriptional co repressor, and is induced by transforming growth factor beta (TGF beta) to repress TGF beta receptor II gene expression. This gene exhibits imprinted expression from the maternal allele in embryonic and extra embryonic tissues.

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Description

Could be E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates

A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis

TPIP is a member of a large class of membrane-associated phosphatases with substrate specificity for the 3-position phosphate of inositol phospholipids

possibly targeting them for degradation

Diameter×depth:87×68×52mm

KLF14 Polyclonal Antibody, 100ul Peptide Synthesis Could be E3 ubiquitin-protein ligaseThis intronless gene encodes a member of the Kruppel like family of transcription factors. The encoded protein functions as a transcriptional co repressor, and is induced by transforming growth factor beta (TGF beta) to repress TGF beta receptor II gene expression. This gene exhibits imprinted expression from the maternal allele in embryonic and extra embryonic tissues.

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