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TNR19 Polyclonal Antibody, 20ul Metabolic enzymes tool compounds Cubilin (CUBN) acts as a

SKU: 47038160981

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TNR19 Polyclonal Antibody, 20ul Metabolic enzymes tool compounds Cubilin (CUBN) acts as aThe protein encoded by this gene is a member of the TNF receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript

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Description

Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes

BMP8B (bone morphogenetic protein 8b) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

Each chain contains a collagen-like region located near the N-terminus

These receptors are heteromeric protein complexes composed of multiple subunits

covalent attachment of UBLs does not result in degradation of the modified proteins

TNR19 Polyclonal Antibody, 20ul Metabolic enzymes tool compounds Cubilin (CUBN) acts as aThe protein encoded by this gene is a member of the TNF receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript

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