Human Semaphorin 6D, SEMA6D ELISA Kit, 96T Cell fragmentation and collection The alpha chain encoded by

The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain

This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells

The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex

It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia

Human Semaphorin 6D, SEMA6D ELISA Kit, 96T Cell fragmentation and collection The alpha chain encoded byShows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections.