Porcine Erythropoietin, EPO ELISA Kit, 96T Liquid Handling ＆Storage |NF-kappa-B is a pleiotropic transcription

|NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation| immunity| differentiation| cell growth| tumorigenesis and apoptosis

The preproprotein encoded by CACNA2D1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1) is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex

Polymorphism within this gene is associated with variable ability to metabolize mephenytoin

from dorsal root ganglion explants in which growth cone collapse was observed

Allelic variants of this gene have been associated with autism and addiction vulnerability

Porcine Erythropoietin, EPO ELISA Kit, 96T Liquid Handling ＆Storage |NF-kappa-B is a pleiotropic transcriptionHormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.