DAPK1(Phospho Ser308) Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) Guanine nucleotide-binding proteins (G proteins)

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems

Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes| or E1s| ubiquitin-conjugating enzymes| or E2s| and ubiquitin-protein ligases| or E3s

thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery

The encoded protein also plays a role in the repression of inflammatory genes as a component of the IFN-gamma-activated inhibitor of translation (GAIT) complex

The encoded protein may bind copper

DAPK1(Phospho Ser308) Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) Guanine nucleotide-binding proteins (G proteins)Death associated protein kinase 1 is a positive mediator of gamma interferon induced programmed cell death. DAPK1 encodes a structurally unique 160 kD calmodulin dependent serine threonine kinase that carries 8 ankyrin repeats and 2 putative P loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants.