53BP1 Polyclonal Antibody, 100ul[BT-AP00042] Monoclonal Antibody Preparation chondrogenesis and maintenance of cardiac

chondrogenesis and maintenance of cardiac and skeletal muscle cells

making it ideal for any laboratory setting

22 µm pore size and a PVDF Express Membrane

which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns

Both proteins are widely expressed and contain an amino-terminal kinase domain followed by a central proline/serine rich domain and a highly conserved carboxy-terminal domain

53BP1 Polyclonal Antibody, 100ul[BT-AP00042] Monoclonal Antibody Preparation chondrogenesis and maintenance of cardiacThe p53 binding proteins 53BP1 and 53BP2 (Bbp) bind to the central DNA binding domain of wild type p53, but do not bind mutant p53. The central DNA binding domain of p53 is required for site specific DNA binding and is frequently mutated in malignant tumors. Binding of 53BP1 to the L3 loop of p53 and of 53BP2 to the L2 loop of p53 confirms that the loop is dependent on p53 conformation. Site specific binding also suggests that 53BP1 and 53BP2 are