NF-L Polyclonal Antibody, 50ul[BT-AP05965] Enzymes This protein functions as a

This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis

thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed: 21602804)

The gene may be regulated by androgens and epigenetic mechanisms

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides

NF-L Polyclonal Antibody, 50ul[BT-AP05965] Enzymes This protein functions as aNeurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot Marie Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral