Raf-1 Polyclonal Antibody, 50ul[BT-AP13533] Measuring Instruments lung cancer

lung cancer

Alternatively spliced transcript variants

This protein has strong similarity to Mus musculus and Cricetulus griseus proteins

The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division

While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm

Raf-1 Polyclonal Antibody, 50ul[BT-AP13533] Measuring Instruments lung cancerThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.