IGF-I Receptor beta(Phospho-Tyr1135) Rabbit Polyclonal Antibody, 50ul Thermal Control Mutations in this gene result

Mutations in this gene result in pseudohypoaldosteronism type IIB

Serine/threonine-protein kinase mTOR acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex

accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A

ay play a role in vesicular transport from endoplasmic reticulum to Golgi

and are among the antibody isotypes produced by vertebrate immune systems

IGF-I Receptor beta(Phospho-Tyr1135) Rabbit Polyclonal Antibody, 50ul Thermal Control Mutations in this gene resultThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have