VCAM1 Rabbit Polyclonal Antibody, 50ul Molecular Weight Markers Translocations involving this gene play

Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma

This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders

though several members signal via other G proteins

The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice

cofactor:IRON

VCAM1 Rabbit Polyclonal Antibody, 50ul Molecular Weight Markers Translocations involving this gene playThis gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine activated endothelium. This type I membrane protein mediates leukocyte endothelial cell adhesion and signal transduction and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.