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Ku-70 Polyclonal Antibody, 50ul[BT-AP04897] In vitro Assessment transcriptional regulation and possibly in

SKU: 48008393657

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Ku-70 Polyclonal Antibody, 50ul[BT-AP04897] In vitro Assessment transcriptional regulation and possibly inThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

transcriptional regulation and possibly in chromatin structure modification

This isozyme is also a selenoprotein

Belongs to the MIA/OTOR family

The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors

The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity

Ku-70 Polyclonal Antibody, 50ul[BT-AP04897] In vitro Assessment transcriptional regulation and possibly inThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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