NMRL1 Rabbit Polyclonal Antibody, 50ul Enzyme Activity Assays MARK1 is a Protein Coding

MARK1 is a Protein Coding gene

Additional isoforms produced by alternative splicing seem to exist

Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney

This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK

it is also required for poly(A) shortening which is the first step in mRNA decay

NMRL1 Rabbit Polyclonal Antibody, 50ul Enzyme Activity Assays MARK1 is a Protein CodingThis gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF kappaB in a ubiquitylation dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3 mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants.