DTBP1 Rabbit Polyclonal Antibody, 100ul Adenovirus Packaging which map to chromosomes 12q13

which map to chromosomes 12q13 and 21q22

Plays an essential role in autophagy

ACC-beta may be involved in the regulation of fatty acid oxidation

The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage

Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity)

DTBP1 Rabbit Polyclonal Antibody, 100ul Adenovirus Packaging which map to chromosomes 12q13This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes platelet dense granules and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome related organelles complex 1 (BLOC 1) and binds to alpha and beta dystrobrevins which are components of the dystrophin associated protein complex (DPC). Mutations in this gene are associated with Hermansky Pudlak syndrome