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Smad3 mouse Monoclonal Antibody(4C9), 20ul Drug Development and Evaluation Polymorphisms in this gene have

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Smad3 mouse Monoclonal Antibody(4C9), 20ul Drug Development and Evaluation Polymorphisms in this gene haveThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of

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Description

Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer

most notably the t (9

GO annotations related to this gene include G-protein coupled receptor activity and opioid receptor activity

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This family member can facilitate growth factor withdrawal-induced apoptosis in T cells

Smad3 mouse Monoclonal Antibody(4C9), 20ul Drug Development and Evaluation Polymorphisms in this gene haveThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of

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