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OAZ3 Polyclonal Antibody, 100ul Miscellaneous |subunit:Component of the NF-kappa-B RelB-p52

SKU: 48404188793

4.6
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OAZ3 Polyclonal Antibody, 100ul Miscellaneous |subunit:Component of the NF-kappa-B RelB-p52The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit.

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Description

|subunit:Component of the NF-kappa-B RelB-p52 complex

likely retains its substrate binding capability

also known as neuralized-like protein 4

Alternative splicing of this gene results in three transcript variants encoding different isoforms

This gene has a related pseudogene| which is also present on chromosome 6

OAZ3 Polyclonal Antibody, 100ul Miscellaneous |subunit:Component of the NF-kappa-B RelB-p52The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit.

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