PCAF Polyclonal Antibody, 100ul[BT-AP06968] Petri Dishes Numerous alternatively spliced transcript variants

Numerous alternatively spliced transcript variants encoding different isoforms have been described

cell cycle checkpoint activation

Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF

Guanine nucleotide exchange factors (GEFs)

The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region

PCAF Polyclonal Antibody, 100ul[BT-AP06968] Petri Dishes Numerous alternatively spliced transcript variantsCBP and p300 are large nuclear proteins that bind to many sequence specific factors involved in cell growth and or differentiation, including c jun and the adenoviral oncoprotein E1A. Lysine acetyltransferase 2B encoded by KAT2B associates with p300 CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300 CBP. It has histone acetyl transferase activity with core histones and nucleosome core