Integrin Beta2 Polyclonal Antibody, 20ul[BT-AP04585] Palm Micro Centrifuges Additional alternately spliced variants have

Additional alternately spliced variants have been described but their full-length structure is unknown

resulting in five different isoforms with distinct properties

ATP binding cassette subfamily B member 7 is a member of the MDR/TAP subfamily

DKK3 encodes dickkopf WNT signaling pathway inhibitor 3 that is a member of the dickkopf family

The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation

Integrin Beta2 Polyclonal Antibody, 20ul[BT-AP04585] Palm Micro Centrifuges Additional alternately spliced variants haveITGB2 encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell surface proteins that participate in cell adhesion as well as cell surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.