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DICER Polyclonal Antibody, 100ul RNA Synthesis and has two modified domains

SKU: 48633084453

4.3
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DICER Polyclonal Antibody, 100ul RNA Synthesis and has two modified domainsThis gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

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Description

and has two modified domains that are thought to have lost their calcium binding capability

The core complex associates with MTA2| MBD2| MBD3| MTA1L1| CHD3 and CHD4 to form the nucleosome remodeling and histone deacetylation (NuRD) complex| or with SIN3| SAP18 and SAP30 to form the SIN3 HDAC complex

Negative regulator of ubiquitin like proteins 1 encoded by NUB1 regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation

The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal

Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies

DICER Polyclonal Antibody, 100ul RNA Synthesis and has two modified domainsThis gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

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