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GCKR Polyclonal Antibody, 50ul Human Genome Knockout Libraries Required for normal assembly of

SKU: 48681682857

4.0
DKK162.00 DKK201.00

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GCKR Polyclonal Antibody, 50ul Human Genome Knockout Libraries Required for normal assembly ofGCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity onset diabetes of the young (MODY).

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Description

Required for normal assembly of mitotic spindles

which has increased affinity for huntingtin protein with expanded polyglutamine repeats

and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions

and invasion

FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain

GCKR Polyclonal Antibody, 50ul Human Genome Knockout Libraries Required for normal assembly ofGCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity onset diabetes of the young (MODY).

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