VP37C Rabbit Polyclonal Antibody, 20ul Antibody Humanization Transcript variants with alternative splicing

Transcript variants with alternative splicing in the 5' UTR have been found for this gene

translocation t(3

This protein also interacts with various protein kinases including IRAK1/IRAK

proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten

It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic

VP37C Rabbit Polyclonal Antibody, 20ul Antibody Humanization Transcript variants with alternative splicingVPS37C is a subunit of ESCRT I (endosomal sorting complex required for transport I) a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al. 2005