ZnT-8 Polyclonal Antibody, 100ul Fluorescent Staining The use of alternative in-frame

The use of alternative in-frame AUG start codons results in multiple protein isoforms

Alternative splicing results in a multitude of transcript variants

Defects in this gene are a cause of glutathione synthetase deficiency

are described

The encoded protein contains a B-box/coiled-coil motif

ZnT-8 Polyclonal Antibody, 100ul Fluorescent Staining The use of alternative in-frameZinc transporter 8 encoded by SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin secreting INS 1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin dependent