HXB3 Polyclonal Antibody, 20ul Liquid Handling ＆Storage |The C-terminus of p100 might

|The C-terminus of p100 might be involved in cytoplasmic retention| inhibition of DNA-binding by p52 homodimers| and/or transcription activation

also known as Simpson dysmorphia syndrome

Very low expression in other tissues such as heart

Several transcript variants encoding many different isoforms have been found for EDA

Homologous genes are found in all three eukaryotic phyla

HXB3 Polyclonal Antibody, 20ul Liquid Handling ＆Storage |The C-terminus of p100 mightThis gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).