TRAP240 Polyclonal Antibody, 20ul[BT-AP09183] Digital Burette Mutations in this gene are

Mutations in this gene are associated with several congenital defects

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which possess E3 ubiquitin ligase activity

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Four alternatively spliced transcript variants encoding the same protein exist for this gene

TRAP240 Polyclonal Antibody, 20ul[BT-AP09183] Digital Burette Mutations in this gene areMED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre initiation complex.