ZFP37 Rabbit Polyclonal Antibody, 100ul Cell Culture Plates Mutations causing Bloom syndrome delete

Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity

The encoded protein is a strong inducer of lymphocyte apoptosis

endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins

and due to amplification

The encoded protein contains an N-terminal EF-hand domain

ZFP37 Rabbit Polyclonal Antibody, 100ul Cell Culture Plates Mutations causing Bloom syndrome deleteThis gene encodes a transcription factor that belongs to a large family of zinc finger proteins. A similar protein in mouse is thought to play a role in regulating the structures of the nucleolus and centromere in neurons. Alternate splicing results in multiple transcript variants.