GBP2 Polyclonal Antibody, 100ul Vessels SPHK2 (sphingosine kinase 2) encodes

SPHK2 (sphingosine kinase 2) encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate

and is also secreted

May be involved in regulation of some genes in gonads

Multiple alternatively spliced transcript variants have been determined for this gene

AHA-1 regulates HSP 90 by influencing the conformational state of the "ATP lid" and consequent N-terminal dimerization

GBP2 Polyclonal Antibody, 100ul Vessels SPHK2 (sphingosine kinase 2) encodesThis gene belongs to the guanine binding protein (GBP) family, which includes interferon induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas.