Rho G Polyclonal Antibody, 100ul Pipette Controller Cytochrome P450 family 21 subfamily

Cytochrome P450 family 21 subfamily A member 2 localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position

The genome has two identical copies of this gene within a palindromic region

Functional studies indicate that both human paralogs associate with the endosomal compartments

This gene encodes the alpha chain of type XIV collagen

Mutations in this gene are

Rho G Polyclonal Antibody, 100ul Pipette Controller Cytochrome P450 family 21 subfamilyRHOG encodes a member of the Rho family of small GTPases, which cycle between inactive GDP bound and active GTP bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma